American Society for Clinical Pathology (ASCP) Histotechnician Certification Practice Exam

Which blood specimen test does NOT require the specimen to be transported in a mix of ice and water?

1. Amylase

2. Cold agglutinins

3. Cryofibrogen

4. Lactate dehydrogenase

The correct answer is: Amylase

The process of transporting blood specimens under specific conditions is critical to ensure the stability and integrity of the samples for accurate testing. In the context of the given question, the test for amylase does not require the specimen to be transported in a mix of ice and water. Amylase is an enzyme that breaks down carbohydrates and is often measured to assess pancreatic function among other conditions. The stability of amylase activity does not require cold storage; it can be reliably processed and transported at room temperature for several hours without significant degradation. On the other hand, tests like cold agglutinins and cryofibrinogen specifically require cold temperatures for transport, as they are sensitive to temperature changes that could alter the results. Lactate dehydrogenase, while it may not require ice immediately, is often best maintained under cooler conditions to prevent any enzymatic activity that could affect the results. Thus, amylase remains stable at room temperature, validating it as the correct choice in this scenario.