American Society for Clinical Pathology (ASCP) Histotechnician Certification Practice Exam

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For a 24-hour urine test, what is the most advisable fluid intake prior to the collection of the specimen?

  1. Half a liter of soda

  2. Up to 24 fluid ounces of water

  3. One liter of fruit juice

  4. Only the minimum needed to quench thirst

The correct answer is: Up to 24 fluid ounces of water

For a 24-hour urine test, maintaining proper hydration is crucial to ensure accurate results. The recommended fluid intake of up to 24 fluid ounces of water prior to the collection helps to adequately prepare the body, promoting normal kidney function and urine production without overwhelming the urinary system with excessive volume or potential contaminants. Water is a neutral fluid that does not introduce any sugars, acids, or potential substances that could interfere with the results, making it ideal as a pre-collection fluid. It supports the kidneys in concentrating urine appropriately during the collection period, allowing for a representative sampling of metabolic waste over the 24 hours. Choosing other beverages like soda or fruit juice can introduce variables such as sugars, dyes, or other substances that could affect the test results and complicate interpretation. Therefore, a controlled intake of plain water up to the recommended amount ensures both hydration and accuracy in urine testing.